ANALYSIS CANNABINOIDS / POTENCY

Cannabinoids are chemical compounds found in cannabis that affect the user by interacting with specific receptors in the central nervous system. There are over 100 different cannabinoids reported in scientific literature, each having a unique biological effect. The composition and potency of cannabinoids vary between strains and are impacted through the cultivation, harvesting, and processing of the plant.

The accurate analysis of cannabis strains and their respective cannabinoid ratios, such as THC to CBD, allow individuals to properly determine a particular product’s efficacy and application. Viridis Laboratories extensive cannabinoid profiling reinforces expectations within the cultivation and manufacturing processes. And with this higher level confirmation of strain identity, brings additional confidence for the consumer.

Delta-9-tetrahydrocannabinol (Δ9-THC)

Delta-9-tetrahydrocannabinol (Δ9-THC)

Delta-9-tetrahydrocannabinol (Δ9-THC) is a psychotropic cannabinoid and is one of the most commonly found cannabinoids in cannabis and gives one a euphoric felling. THC is one of few psychoactive cannabinoids that binds to CB1 & CB2 receptors in the body.  This can produce a wide-range of biological and behavioral responses which can provide health and enjoyment benefits.

Cannabidiol (CBD)

Cannabidiol (CBD)

Cannabidiol (CBD) is considered the second most researched cannabinoid in cannabis. CBD is a non-psychoactive cannabinoid that doesn’t have the same intoxicating psychoactive effects as Δ9-THC. CBD has been found to interact with a variety of different biological targets, including cannabinoid receptors and other neurotransmitter receptors.

Acid Cannabinoid (CBDA)

Acid Cannabinoid (CBDA)

Acid cannabinoids (CBDA), in the presence of specific enzymes, are converted into specific acids during the growth of the cannabis plant.

Acid cannabinoids (CBDA) can also be transformed into active cannabinoids (CBD) given a decarboxylation step (heating cannabinoids at specific temperatures).

Δ8-Tetrahydrocannibol (Δ8-THC)

Δ8-Tetrahydrocannibol (Δ8-THC)

Of the compounds within cannabis, the most often cited is Delta-9 Tetrahydrocannabinol.  Through an aging process, this compound oxidizes into an isomer known as Δ8-THC. These two phytocannabinoids are analogs that share the same structural formula but have a slightly different arrangement of atoms. The molecular similarities provide similar therapeutic avenues with different psychoactive effects.  Because this lesser-known cannabinoid is created through oxidation, the resulting molecule is stable when exposed to air. This makes it an interesting compound for use in pharmaceutical applications.

Cannabinol (CBN)

Cannabinol (CBN)

Cannabinol (CBN) is a cannabinoid and effective compound that contributes to cannabis’ effects on the body and mind. CBN works as a psychoactive compound like THC does, but it has a milder impact. The reason for this is as TCH begins aging, it begins transforming into CBN. The benefit of this is, CBN mainly activates the CB2 receptors, which affect the immune system. It also interacts with the CB1 receptors to a lesser degree which work with the central nervous system.

Acid Cannabinoids (CBGA)

Acid Cannabinoids - CBGA

Acid Cannabinoids (CBGA), in the presence of specific enzymes, are converted into specific acids during the growth of the cannabis plant. For instance, The THCA synthase enzyme converts CBGA to tetrahydrocannabinolic acid within a catalytic step.

Acid cannabinoids (CBGA) can also be transformed into active cannabinoids (CBG) given a decarboxylation step (heating cannabinoids at specific temperatures).

Cannabigerol (CBG)

Cannabigerol - CBG

Cannabigerol (CBG) is a non-psychoactive cannabinoid typically most abundant in low-THC, high-CBD cannabis strains. Like THC, CBG reacts with the cannabinoid receptors in the brain. It is known to be the only cannabinoid with the ability to stimulate the growth of new brain cells. CBG, however, acts as a buffer to the psychoactivity of THC, by working to alleviate the paranoia sometimes caused by higher levels of THC.

Cannabicyclol (CBL)

Cannabicyclol (CBL)

Cannabicyclol, also called CBL, is one of the least known and studied cannabinoids in the cannabis plant. Although it is commonly found in many varieties, in particular those with a higher content of CBC (Cannabichromene), the amount of CBL produced in trichomes is always very low, so it doesn’t usually receive the attention given to other, more plentiful compounds of the plant with a much more noticeable presence, such as THC, CBD or CBN.

One of the main characteristics of CBL is the absence of psychoactivity in its effect. In fact, CBL shares its formula with many of the other phytocannabinoids produced by cannabis, even with psychoactive compounds, although it differs slightly in its structure meaning that its effects vary enormously.

Acid Cannabinoids (CBCA)

Acid Cannabinoids - CBCA

Acid Cannabinoids (CBCA), in the presence of specific enzymes, are converted into specific acids during the growth of the cannabis plant. For instance, The THCA synthase enzyme converts CBGA to tetrahydrocannabinolic acid within a catalytic step.

Acid cannabinoids (CBCA) can also be transformed into active cannabinoids (CBC) given a decarboxylation step (heating cannabinoids at specific temperatures).

Cannabichromene (CBC)

Cannabichromene (CBC)

Cannabichromene (CBC) is non-psychoactive and although considered one of the “big six” cannabinoids prominent in medical research, it doesn’t get as much attention. However, CBC’s benefits are extremely promising and is considered the third most common cannabinoid found in cannabis. In some cannabis strains it can even exceed the cannabidiol (CBD) content. CBC predominantly interacts on TRPV1 and TRPA1 receptors and has many properties that can have a positive effect on one’s health.

Cannabidivarin (CBDV)

Cannabidivarin (CBDV)

Cannabidivarin (CBDV) is a non-psychoactive cannabinoid that will not cause the euphoric effect that TCH provides. It is found more prevalently in indica strains, specifically landrace indica strains, and strains that are lower in tetrahydrocannabinol (THC).

Cannabidivarin (CBDVA)

Cannabidivarin (CBDVA)

Acid Cannabinoids (CBDVA), in the presence of specific enzymes, are converted into specific acids during the growth of the cannabis plant. For instance, The THCA synthase enzyme converts CBGA to tetrahydrocannabinolic acid within a catalytic step.

Acid cannabinoids (CBDVA) can also be transformed into active cannabinoids (CBDV) given a decarboxylation step (heating cannabinoids at specific temperatures).

Δ9-Tetrahydrocannabivarin (Δ9-THCV or simply THCV)

Δ9-Tetrahydrocannabivarin (Δ9-THCV or simply THCV)

Δ9-Tetrahydrocannabivarin (Δ9-THCV or simply THCV) is a homolog of THC, and therefore these two cannabinoids have very similar chemical structures. It has been said that in small quantities THCV acts as an THC cannabinoid antagonist (THCV reduces THC effects), but in larger quantities THCV acts as a THC agonist (it bolsters or enhances its effects). THCV is found in high concentrations in African sativas.

Delta-9-tetrahydrocannabinolic acid (Δ9-THCA)

Delta-9-tetrahydrocannabinolic acid (Δ9-THCA)

Delta-9-tetrahydrocannabinolic acid (Δ9-THCA), in the presence of specific enzymes, are converted into specific acids during the growth of the cannabis plant. For instance, The THCA synthase enzyme converts CBGA to tetrahydrocannabinolic acid within a catalytic step.

Since CBGA is converted to other acid cannabinoids during cannabis growth, it is commonly referred to as a “parental” cannabinoid. Acid cannabinoids (CBDA, CBCA, CBGA and THCA) can also be transformed into active cannabinoids (CBD, CBC, CBG, THC) given a decarboxylation step (heating cannabinoids at specific temperatures).

Delta-9-tetrahydrocannabinolic acid (Δ9-THCVA)

Delta-9-tetrahydrocannabinolic acid (Δ9-THCVA)

Delta-9-tetrahydrocannabinolic acid (Δ9-THCVA), in the presence of specific enzymes, are converted into specific acids during the growth of the cannabis plant. For instance, The THCA synthase enzyme converts CBGA to tetrahydrocannabinolic acid within a catalytic step.

Acid cannabinoids (Δ9-THCVA) can also be transformed into active cannabinoids (Δ9-THCV) given a decarboxylation step (heating cannabinoids at specific temperatures).